Antidepressants Looking Worse and Worse

More and more information is coming out about SSRIs (the overwhelming majority of antidepressants) and their adverse effects. Now it is increased risk of stroke and/or heart attack, particularly in men and even more particularly in middle aged men. The reason? Messing around with serotonin, just like cause of most of the other bad effects from antidepressant use. It seems that messing around with serotonin causes constriction of blood flow. Specifically, the theory is that higher levels of serotonin and norepinephrine causes atherosclerosis.

This was not seen in studies of the older type antidepressants (now almost completely out of use because of the newer and more popular SSRIs). However, there is a reason the older antidepressants fell from popularity too. They also had major side effects, some of them deadly as well.

Now there is a new drug out for a new “medical disorder”. If you feel tired because you do shift work, then according to the makers of this new drug you should take a pill for it and feel all better. No telling what sort of effects this drug will be found to have years from now.

It seems clear that this culture of “have a problem – take a pill” has some serious flaws. Perhaps it is time to rethink how we approach our health and health care, such as eating better, taking preventative measures instead of waiting for something to go wrong and then address it and things of that sort.

New Information on Antidepressants

Anyone who has had a bad experience with an antidepressant or anti-anxiety medication will find the results of a recent study no surprise. What may be of surprise is that the effects continue long after the medication is stopped. In this particular case it is SSRI (Selective Serotonin Reuptake Inhibitors) drugs, which is basically all antidepressants. They affect the brain’s plasticity, causing real physiological changes that are long-term.

In this particular study the researchers used Prozac and showed that long-term treatment with this drug (an SSRI) caused changes to one of the main types of neuronal cells in the hippocampus. These cells are called granule cells and it also affected their connection to other neuronal cells. The researchers say the cells seem to undergo “serotonin-dependent dematuration” that reversed adult plasticity to an immature state. The changes were shown to be associated with increased anxiety and also periods of alternating hyper and/or hypo activity.

One of the researchers said that some of the side effects experienced by humans taking these drugs, such as anxiety and switching behavioral patterns, could be because of the excessive dematuration of granule cells in the hippocampus.

I’ve already mentioned before in previous posts my bad experiences with SSRI drugs and anti-anxiety drugs that I was placed on so the results of this study really didn’t surprise me. I certainly wasn’t happy to learn that the effects on the brain continue long after the drugs are stopped though. Personally, as bad as my experiences were with some of the antidepressants they placed me on were, they paled in comparison with the nightmare of being placed on Klonopin and then trying to wean off of it. I believe that Klonopin and other benzos are absolutely some of the worst drugs one can be placed on. Just Google “Klonopin withdrawals” and you will find that there are literally countless stories of hellish experiences associated with this drug. I can tell you that they are not exaggerating. Trying to come off this drug is hellish and takes a long, long time. The longer you are on it and the higher the dose, the longer and worse the withdrawals. The official rate of withdrawal as stated on the manufacturer’s own website is completely intolerable for myself and anyone I have ever talked to about it. You have to go much slower. You certainly cannot just stop cold turkey unless you want to end up in the E.R.

I realize that some people may be helped by SSRI antidepressant drugs. But I wasn’t. And if they really worked like they are advertised to then there would not be any depressed people. Simple logic. The fact is they don’t work much of the time. Other studies have shown that they are actually useless and it is a placebo effect that helps people. Still other studies show that meditation and exercise and dietary changes are just as, if not more, effective in treating depression as these drugs that alter brain chemistry and have long term effects even after they are stopped.

After 9 solid years of being treated with drugs and shrinks I was no better. So I know they don’t work like the miracle pills they are touted as. It took a completely different approach, no drugs involved, to help me. So please inform yourself about these drugs and read the labels carefully and talk to your doctor if you or a loved one are about to be placed on drugs. Pills are not always the answer!

Depression Defeated!

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I have mentioned in previous posts my struggle with depression. I have also mentioned how the Western method of treatment (take a pill, see a shrink) had completely failed me. After this latest bout of depression which lasted a full 9 years and defied all the effort of Western medicine (change pills, up the dose, add another pill, see a different and more expensive shrink) I had had enough. I have taken a different route and this works! Astonishingly fast too I might add. I know I can’t be the only one that has gone through this. I cannot be the only one who has been told they have “Treatment Resistant Depression” or the term would have never been coined. Further, if pills worked for everyone then why is there anyone with depression at all? The fact is, pills do not work for everyone. Neither does seeing expensive shrinks.

I decided to write about my experience. The failure of the Western medical approach and the incredible speed and effectiveness of an “alternative” approach. I really hate the term “alternative” as it can invoke feelings of doubt in some people, as if it were some inept and crazy thing. It’s not. It’s far older and thus more mature than our system. In fact, it works so well that now pharmaceutical companies are producing and selling “pharmaceutical grade” compounds and pills of the exact same things this “alternative” method uses! So they know it works and you can be sure that the “pharmaceutical” version of these things are far and away more expensive than what works without being labeled pharmaceutical.

The approach is Traditional Chinese Medicine (TCM) and Naturopathy. I don’t see it as simply an “alternative” approach, I see it as different. And in my case, effective whereas the accepted and standard treatment was a complete failure.

Anyway, the amazing success this different approach has had in helping me get my life back and freeing me from the darkness of depression has prompted me to write a short book about it. I wrote the book with depressed people in mind because when I was in the grip of depression I tried to read several books that were supposed to help me only to find I couldn’t get through them. They were too long and I had to read through too much useless “filler” to get to any useful information. So I made this book short and to the point. It gets right to the things that worked for me and covers some of the problems one can encounter with prolonged severe depression, including the financial impact. The book is available at Amazon. I’m selling it for ninety nine cents so it’s not as if I’m trying to get rich from it. I truly do want people to benefit from it. I could just give it away, and I thought of that, but I figured that ninety nine cents was a reasonable price and it will help me and my son keep this blog going.

Exciting News about Yoga

As I stated in an earlier post, I’ve tried yoga but just couldn’t seem to get into it. I practice tai chi every day and enjoy it, but it seems that quite a bit of strong evidence is pointing in the direction that yoga may in fact be superior, at least when it comes to psychological health. Many of the drugs used to treat anxiety directly affect the extremely important neurotransmitter GABA. GABA levels that are out of whack can cause all kinds of problems such as depression and especially anxiety.

It seems that yoga has a more profound effect on GABA levels than other forms of exercise such as walking. One of the studies can be found here. There are many others as I found after reading that one simply by Googling yoga + GABA. So, I think it’s time for me to give yoga another shot.

I know in my last post I mentioned that I was going to go further into the actual practice of zazen and also moving meditations such as tai chi, and I haven’t forgotten but things have been rather… crazy. I will indeed go into those subjects but wanted to write about this first as I found it very interesting and promising. So I have decided to try yoga again and give it some time to see if there are any positive effects. I will be writing about any experiences, good or bad, that I have with it.

Have a great day!

Namo Amituofo

More Light on GAD, Stress and Meditation

My previous post was about stress and the severe damage unrelenting or uncontrolled stress does. It turns out that there are many ways to deal with stress but the rate of success may depend on whether or not your stress is caused by an external (environmental or situational) trigger. If you have something such as major depression, GAD (Generalized Anxiety Disorder), hypochondria or any other problem that keeps you on edge constantly then it is obviously more difficult as these problems alone cause almost constant stress in the form of severe anxiety and/or worry and are made even worse when life itself becomes stressful.

If you don’t have any of the aforementioned problems and stress is wreaking havoc in your life then the chances are good that you can deal with the stress simply by removing yourself from the stress-inducing problem or environment. If that is not possible then meditation, yoga, tai chi, eating well, getting enough rest and so on can keep the stress manageable. Consider yourself lucky if you are not also plagued by one or more of the above mentioned problems as well.

If you do have one of the problems mentioned above, obviously things are different. The problem is then not one you can simply remove yourself from. The problem is within. This throws a whole new twist on things. You can still use the methods mentioned above and get some relief, but sometimes the problem just can’t be cured (references at the end of the post). What I mean by cured is that if you take the traditional method of drugs and therapy, sometimes it simply fails. Then what? Then you have to start looking for different approaches. As I mentioned in my post about depression, Western approaches have completely failed me. I am having to take another route. Don’t be fooled into thinking that the Western way is the only way. If it works for you then great, but if it doesn’t, don’t be afraid to look elsewhere.

There are all kinds of studies that show the many benefits of meditation, so it is probably no surprise that it can most definitely help with anxiety problems. What is new and so less widely known is that it has now been shown to actually help all the way down to the cellular level. Just as stress harms down to the cellular level, meditation helps. There are many ways to meditate, I use several but the one I use the most is sitting meditation. Zazen. It helps. It can make all the difference in the world for me. But I also use moving meditation such as walking meditation and tai chi. I’ve tried yoga but just couldn’t get into it the way I can tai chi. And like yoga, there are many different forms of tai chi. Long forms, short forms and everything in between. The point is, stress is bad and meditation is good. In my next post I will go into more detail about just exactly how to do different meditations, both moving and sitting. It’s something that is incredibly important in my life and I know first hand some of the things it can do to bring some peace into one’s life. I don’t claim to be an expert, nor a doctor… but I do know it has made a difference it my life and so if I can help even one person learn and it help them then the world is that much better.

References regarding GAD and it’s chronic and sometimes incurable nature:

Here, here and here

The Power of Your Mind

There can be no question that the human mind is an awesomely powerful thing. It can help or hurt. It can help bring about or speed up healing and it can also make you sick. Thoughts are important. A single thought can have a dramatic effect on the body, for good or bad. The mind that has been trained to calm almost on demand through meditation can stem off a cascade of negative emotions. The mind out of control can wreak havoc. This is not some dreamed-up, fluff-filled hooey. It’s fact and can be verified, not just in controlled studies but also by daily experience. It’s something meditators have known for centuries, long before the advent of modern science.

The mind can be controlled to an astounding degree. Just recently it was found that people can control single cortical nerve cells with thought! The study and results are fascinating to say the least and can be found here. It has also been shown that peace of mind can “bridge the gap” in well-being for less fortunate (i.e. undereducated, financially disadvantaged and so on) people, just as surely as stress is a killer.

The problem is simple… how do we control the mind and harness it’s amazing power so that it can work for us instead of against us? This is especially crucial for people with an anxiety disorder or depression. I know this personally. The only answer I have found to this problem is meditation coupled with always being aware of what is going through my mind. When I catch myself engaging in a negative thought pattern then I use different methods to stop it. The method depends on the situation and the type of problem. Prayer has also been shown to help. I cannot say that prayer has worked for me but it obviously helps some. So I suppose it depends upon the individual. For me, meditation works so that is what I use. Breath control or manipulation also is effective for me when I am not in a place that I can just drop everything and sit and meditate. It gets me through until I can meditate.

I am learning more and more just how powerful the mind is and it is truly, truly amazing. I learn from my own experience, from reading/studying and from others who are more experienced than I. Everyone is different. We aren’t cookie-cutter, one-size-fits-all. For some it may be prayer, for others sitting meditation, and others from some form of moving meditation such as Tai Chi or Qigong. Others may combine all of the above. My point is, the mind makes all the difference in the world. You don’t have to have an anxiety disorder, depression, PTSD or some other condition to benefit from learning ways to teach your mind to work for you instead of against you. What I can tell you is that it at first requires a monumental dedication and a lot of patience. But it is worth it.

Goals and Dreams

As I mentioned in a recent post, I’ve been reading a very academic and scholarly book on Zen Buddhism. Particularly the Zen of Dogen (the founder of the Soto sect in Japan) and how he (Dogen) lived his religion. The book is a very difficult read simply because it is written in such an academic format. It is not one of those easy-to-read, flowery Zen books that are in {over}abundance here in America. I began to wonder why someone would take the obviously enormous amount of time and effort to write such a book. The book is excellent. Just because it is a difficult read by no means subtracts from it’s information or value. But then it became obvious to me why the author did it. It is important to him. It’s something he is passionate about, otherwise he wouldn’t have spent almost his entire life studying Dogen and his Zen. The author wishes to share what he has discovered, and his passion with the world.

I think it’s the same reason people do anything that takes a great amount of effort and time. Why painters paint, writers write and so on. It’s their passion, it’s the challenge and the reward. The reward is often not monetary. An example is people who climb Mount Everest. Overcoming an obstacle and meeting a challenge can be very much a reward in and of itself. It’s why I’m determined to earn 4th dan. It’s why one of my sons wants to compete in his first amateur MMA competition. It’s why another of my sons learns and studies so much even aside from his college demands. It’s why my youngest wants to compete in a tournament and why my wife continued her education while educating others (she’s a teacher). The challenge, the reward, the focus and the drive. Depression has stolen a lot of time from me, but I’m really feeling the drive to get going again. I want that 4th dan! That’s a good thing because for too long I didn’t much care about much at all because depression had sapped that drive.

People often wonder why others do what they do, personally I’ve always wondered why anyone would want to climb Mount Everest. But it must be the drive, the passion. Reaching a point they haven’t yet reached. “Because it’s there!” So it doesn’t matter if it’s writing a book, competing in MMA, reaching 4th dan, constantly learning, trying or even creating new recipes, or whatever the goal is, I think the same thing is behind it all. A determination to go beyond what is already achieved and the reward of doing so. Passion. Wanting to share with others. I think everyone has something they want to achieve, even if it is simply being happy with what they already have achieved :-) . Others may find whatever it is someone deeply wants to accomplish strange or even trivial, but what an extremely dull and boring world it would be if nobody did anything different. What a bland and utterly uninteresting world it would be if people never followed their dreams. Now that I am getting my drive and focus back, I remember what it’s like to keep pushing toward a goal that nobody else seems to understand. I don’t understand a lot of other peoples’ goals and dreams, but I hope I’ve learned now to never make the mistake of trivializing them whether I understand them or not.

Actions or Words?

I read or heard somewhere that people remember you for how you made them feel, not for what you said. With the exception of some great speakers and novelists I imagine this is very true because memory can be a tricky thing, so words can get mixed up in the fog of time. But how a person made me feel, whether good or bad, I remember. This has been something I’ve been reflecting on quite a bit lately… how I’ve made others feel in the past and how I am making those feel that are in my life now. A lot of guilt is part and parcel of depression I’ve been told, so I’m learning to realize that I can’t go back and “fix” what I’ve done that hurt people in the past. I can however make sure I don’t make those mistakes again. I can also focus on here and now and be aware of how I am making others feel in the present.

I think of my wife, my sons, my parents, my sister and her family and others as well and try to think of ways to let them know that I am very thankful and grateful that I have them in my life. I contemplate on how I may have made them feel in the past and how I can take steps to make their life happier. And it’s not just them, how I treat the cashier at the store, the waiter or waitress or the people who live down the road… it makes a difference in their day as well.

I realized I am a very reactionary person. If someone was rude to me, I reacted immediately, without even thinking about it, just tear into the person for being rude. I also realized that very reaction not only just made my day worse but also theirs. Nobody likes to be treated rudely, but most of the time reacting the way that, unfortunately, was my habit didn’t help matters any. It didn’t make the person treat me nicer the next time I saw them. Sure, they may have been silent the next time but their dislike for me was noticeable. It was still an uncomfortable experience. I’m finding it’s much better to just walk away, at least most of the time. That way my anger doesn’t escalate by engaging the person in a verbal brawl and I can let the matter go far more easily and not carry it around with me all day. Of course that’s easier said than done, but I’m working on it.

The point of this short post is simply that I believe what I read or heard about people remembering you for how you made them feel instead of what you say is true. It doesn’t matter if one can walk around giving flowery speeches and flattering words if the person’s actions tell an entirely different story. So I’m trying to be more aware of how I am making people feel. The old saying that actions speak louder than words seems all the more true when I think about this. Who knows, maybe by being more aware of how my actions are affecting people, I might just become a better person along the way. That would be a good thing!

Counting My Blessings

I have been counting my blessings since my post about depression. Depression seems to make everything seem dark and gloomy, as if there is no possible hope. It robs you of the recognition that you have many things to be thankful and grateful for. It’s as if it places a filter in your mind that only allows dark, gloomy thoughts to register. But, now that I have begun training my mind as I should, exercising my body, trying to eat better and recognizing the bombardment of gloomy thoughts for what they are, I am feeling hope. I know better than to proclaim victory and become complacent, I’ve been here before and I know all too well that if you let up for an instant, especially if something stressful is suddenly thrown into the mix, you can fall right back down to where you were or even lower.

As I stated in my post about my depression, Western medicine has completely failed. What’s more, just today as I was reading an article on the Internet an ad was on the page. It said something to the effect of, “Not responding to depression treatment? Click here for help.” So, I opened the ad in a new tab just out of curiosity to see what they had to say. I had to laugh when I read it. It was an ad by a major drug company claiming that if you weren’t getting better on the pill(s) you are currently on, that their drug had been “proven” to be effective when added to your already existing drug(s)! I found that both hilarious and troubling at the same time. In essence what they are saying is, “Hey, through another chemical at it! Buy ours and add it to the chemicals you are already on!”. Ridiculous.

So, I have been following the advice of my TCM practitioner, taking the natural substances he told me to. Following his instructions about exercise, nutrition and other things and guess what… I feel better! The withdrawal and weaning process of coming off the powerful chemicals that Western medicine put me on is hellish and slow, but I have to get off that stuff. I have noticed that by following the advice of my TCM practitioner my mind is not as foggy. The real litmus test, and proof that things actually are improving is that my wife has noticed a difference. The TCM (Traditional Chinese Medicine) practitioner had told me to ask her to monitor me because I needed an objective view on how things are going. I don’t think I could do this without the help and support of my loved ones.

So, I’m counting my blessings. I’m so grateful and thankful for the help and support of my wife, my parents, my kids and from readers of this blog who have emailed me with their help and advice (you know who you are and thank you very much :-) ). Here is a short list of things and people I’m making sure I remember each day how lucky I am to have in my life:

  • My wife
  • My sons
  • My parents
  • A roof over my head and food to eat
  • My TCM practitioner
  • The will and determination to get better
  • Forgiveness and the ability to let go
  • Tae Kwon Moo Do
  • Readers of this blog who have helped (are helping) via email
  • Learning to live right here and right now. Not getting hung up in the past or lost in worry about the future. Easier said than done, but I’m working on it!

And many, many more things.

Here is a short list of what I am throwing (or in the process of ridding myself of) out of my life:

  • Anger
  • Self-loathing and self-hatred
  • Worry
  • Grudges
  • Greed (feeling I have to have this or that when I actually already have so much to be thankful for)
  • The drugs I was placed on
  • And the one that’s going to get the hardest kick of all… Depression

Of course everyone has worry and anger at times. But they will no longer have any lingering and/or significant role in my life. I’ve wasted far too much time on those already.

To my wife, my sons, my parents and to those readers who have contacted me and helped me, this post is really for you. This is a “Thank You” post. Please know that by being there, helping, letting me know that I really can beat the depression that has dragged me down you have made a difference. More than I can put into words and more than you know. Thank you!!

Depression

I have debated whether or not to address this issue because it is so personal, but after discussing it with my wife I have decided to go ahead and do it because, as she pointed out, if helps even a single person it will have been worth it.

For a very long time (years) I have lived with depression. I have tried everything, doctors, therapists, psychiatrists and their drugs. Nothing has helped. In fact, to be quite frank about it, their drugs have only made things worse. My life is much more complicated and difficult now since being on the drugs than it was before the drugs. One of the drugs is extremely addicting and has wreaked havoc with not only the addiction but also its horrible side effects. I have been on that particular drug for years now. When I knew I had to start trying to get off of it, I was shocked when there was no plan or guidance given on how to get off of it safely. Coming off this drug cold turkey will land you in an ER, or worse it could actually kill you.

The weaning process is slow and hellish. I have been able to wean down to half the dose I was on. Still a high dose though. I had to stop weaning for a while because I simply couldn’t take it any longer. Now, I start that process all over again, hopefully to get free of it for good. I do not look forward to the effects of weaning off! I know what awaits me. But I need to be free of this drug. It has reversed my sleep pattern, keeps my stomach in constant turmoil, makes me feel “drugged” or “doped” all the time as if my mind is in a fog that never lifts. Coming off of it causes its own symptoms. Intense stomach problems, intense nervousness/anxiety, confusion, nightmares and more. And that’s tapering off even slower than what is “recommended” as a safe pace. Any faster is dangerous. The “recommended” pace is intolerable. The drug is Klonopin. NEVER allow yourself or anyone you love to be put on this highly addictive drug.

With the failure of conventional (or traditional, or Western) medicine to help me, and with their treatments actually making things worse I am now trying a different approach. Traditional Chinese Medicine (TCM), acupuncture and Naturopathy. I cannot start with the acupuncture treatment for depression until I am off the Klonopin because the drug interferes with effective treatment. But I can use acupuncture to help me get off the drug. I am also using Tae Kwon Moo Do, Tai Chi and other methods of exercise and stretching. More sunlight is also a must (since my days and nights are reversed as a result of the Klonopin). Diet is also to play a big role in my recover. More than I thought! Now I have even more reason to go vegetarian!

I remember a few years ago, my primary doc told me she had discussed my situation (not responding to treatment) with a high-ranking psychiatrist who traveled the nation teaching other psychiatrists and giving seminars. My doc did not of course name me, but did describe my situation. The “shrink of shrinks”, as I like to refer to the high-ranking psychiatrist, told my doc that severely depressed people seem to be low in the B vitamins (particularly B12) and folic acid. Whether this is a result of the depression or a cause I don’t know. Nor do I care. If I need it, I need it. It’s like the debate within Western medicine of biological causation of depression or environmental. Perhaps it is the depression itself that causes the biological “mess-up” of chemicals in the brain and not the other way around.

When I went to the acupuncturist/TCM practitioner, he “prescribed” exactly what the shrink-of-shrinks had told my doc. B-Complex (heavy on the B-12) and folic acid. He said the Chinese have known this all along. I believe him. I didn’t tell him about the shrink-of-shrinks recommendation of it, he brought it up himself. So it seems as if Western medicine is starting to, at least to some degree, realize that TCM is valid. I know of a woman that was dying of cancer and was given the choice of going home to die or stay in the hospital. She went home. Her father refused to accept that she should just die and brought in help from China, and also other TCM practitioners. She had gone through the entire regiment of cancer treatment in the Western style of medicine, and it combined with the cancer had left her extremely weak and frail. The TCM combined with meditation, visualization, sunlight exposure and when she could, “soft” styles of traditional Chinese martial arts forms. She didn’t die! In fact, she is still alive today and teaching martial arts! The Western doctors had told her that she would be dead within weeks. They even went so far as to try to sue the Chinese doctors and TCM practitioners. Why would the Western doctors do that? Simple. They were embarrassed! TCM saved her life where they had failed. You can read her incredible and very moving story here and learn more about her life today here.

I also know of another woman, whom I met once at a business meeting, who was diagnosed with breast cancer years ago. Doctors were urging aggressive and extreme measure to combat it and save her life. She thought about it and came to the decision that there had to be another way. There was, she found it, and is alive and very busy today. You can find out more about her and her story here and here. An astounding and disturbing part of her story is that she has written a book about her recovery and journey to wellness, but because of the power Western medicine wields, the book is tied up in legal battles over what she can and cannot say. This is absurd! People get better and live using a different approach than that of Western medicine and instead of trying to learn from it and help others, pharmaceutical companies, some doctors and others try to silence these individuals! This behavior is not only wrong, it is harmful and negligent. (I hope my web host has the intestinal fortitude to not cave to any pressure this post may bring, if they do not I will certainly move to another. I will not have free speech trampled upon)

I am not saying all Western doctors are bad, nor am I saying that Western medicine as a whole is a failure. It is not. It has saved lives. But it is not the answer to everything. And when it fails, other approaches and treatments should not be discouraged or belittled. Especially when those other approaches and treatments have proved time and again to be effective and often have far less (if any) side effects.

I have read about and known of too many people that have died from severe depression, whether it be by suicide or just being so worn down from it that an illness that should not have been fatal, was. Depression affects not only the mind and brain, but also the body. People who have never had a severe depression cannot know what the depressed person is going through. It is a living hell. A heavy darkness that does not lift. A living nightmare. It makes even the smallest of tasks an enormous effort. It is a killer. A slow, methodical, insidious and merciless killer.

This is my story. Western medicine has failed me. Their drugs have made things worse, not better. Now I turn to a different way. I do not want to become a statistic. I will be posting about my progress from time to time. What works, what doesn’t. For the first time in far, FAR too long I see hope. I see a glimmer of light in this world of darkness that is depression.